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We present a new preprocessing method, PeakSelect, to improve the accuracy and efficiency of Tandem Mass-Spec peptide (protein) identification. The fundamental difference between noise and fragment i...
The assumption on the mass error distribution of fragment ions plays a crucial role in peptide identification by tandem mass spectra. Previous mass error models are the simplistic uniform or normal ...
Shared Peak Count (SPC), i.e. the number of matched peaks between the experimental MS/MS spectrum and the theoretical one predicted from a peptide sequence in the database, is a widely used scoring me...
The correlation among fragment ions in a tandem mass spectrum is crucial in reducing stochastic mismatches for peptide identification by database searching. Until now, an efficient scoring algorithm ...

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